The QSight LC/MS/MS System provides the capability and confidence required to analyze the most complex food and environmental samples. With high level of sensitivity and throughput, laboratories can meet even the most stringent regulatory requirements rapidly, easily, and effectively
| 型号名称 | QSight 420 LC/MS/MS |
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Analytical laboratories face many challenges when analyzing contaminants such as Pesticides, PFAS, mycotoxins in complex matrices. These samples often require time-consuming sample prep and regular maintenance of the analytical technology.
Due to PFAS persistence in the environment and potential health risks, regulations have been undergoing constant change and refinement.
With our extended portfolio of cannabis testing products featuring best-in-class sample homogenization platforms, ICP-MS, LC/MS-MS, Headspace-GCMS, UHPLC and FTIR instruments and consumables, we help drive analytical best practices and operating procedur
PFAS matrix-induced contamination poses various challenges for analytical laboratories, from the risk of achieving low detection limits and lab downtime.
PFAS compounds are ubiquitous throughout the environment and accumulate everywhere, including in the lab.
As per- and polyfluoroalkyl compounds become more prominent, the US Environmental Protection Agency (EPA) are developing more stringent regulations for PFAS monitoring.
Stricter regulations demanding lower detection limits, increased throughput and efficiency demand that labs need an LC/MS/MS solutions that offers robust and reliable performance while ensuring efficiencies.
When examining complex compounds like PFAS, pesticides, and mycotoxins using LC/MS/MS in challenging matrices, laboratories encounter issues such as system contamination, matrix effects, and the laborious task of source cleaning.
The PerkinElmer QSight LC/MS/MS is used for many applications, including forensic toxicology.
In this presentation, prepare to learn all of the best practices for Liquid Chromatography Mass Spectrometry from consumables all the way to instrumentation and analysis. This talk is well-suited for all LC/MS applications including environmental testing
In this latest webinar, LC–MS/MS PerkinElmer expert Dr. Avinash Dalmia describes how LC–MS/MS based systems and methods can overcome the challenges associated with the analysis of pesticides and mycotoxins regulated by Colorado state in hemp with dual ES
Growing environmental concern has led to stricter regulations of drinking water and water supplies over the past decade including routine monitoring and detection of cyanotoxins resulting from ever-growing algae blooms. This talk discusses the utiliza
PerkinElmer offers a portfolio of high-performance solutions to optimize your laboratory workflow for PFAS analysis.
Pharmaceutical and personal care products (PPCPS) are an emerging environmental concern and include human and veterinary prescriptions, over-the-counter medications, sunscreens, lotions, soaps and insect repellents. In this webinar we demonstrate the a
In this podcast, we meet with Simone Rumph, a first generation college student, to discuss her research on post-mortem drug identification.
In this short webinar, PerkinElmer’s Environmental Leader, Tom Hey, discusses simplified PFAS method implementation with the comprehensive PerkinElmer LC/MS/MS workflow, featuring ready-to use consumables kits, reagents and software-driven compliance.
Emerging contaminants, including perfluoroalkyl surfactants (PFAS) and Pharmaceuticals and Personal Care Products (PPCPs), have garnered increasing interest in recent years as their bioaccumulative nature and endocrine disrupting potential have become..
When it comes to analyzing environmental or food samples, including water, soil, cannabis or any solid matrices, labs need to meet stricter regulations that demand lower detection limits.
The US EAP Method 537.1 is used for the determination of selected PFASs in drinking water by solid phase extraction and liquid chromatography/tandem mass spectrometry. This talk discusses the utilization of the PerkinElmer QSight® Triple Quadrupole LC
农药可以通过我们食用的食物对人类健康产生不利影响，也可以渗入土壤和地下水并通过环境影响我们。为了适应复杂且不断变化的监管环境，您的农药分析解决方案需要跟上您不断增长的样本量。
QSight 400与QSight LX50超高效液相色谱仪联用，为实验室提供全新的技术体验，用于分析复杂的食品、药品类和环境类样品。拥有超高的灵敏度和样品通量，实验室可轻松、快速和高效地应对最严格的法规监管要求。
Our modular Simplicity 3Q™ software is ideal for acquiring, quantifying and reporting
Product Certificate for the QSight 300/400 Series
采用珀金埃尔默QSight-LCMSMS分析燕麦片中的草甘膦和类似极性农药。
水溶性维生素（WSV）主要由维生素B复合物组成，是许多食品的基本成分，尤其是在婴儿配方食品中。在分析强化食品时，由于需要符合每日的摄入量，维生素的浓度范围很广，这一点尤其具有挑战性。本应用介绍了一种LC-MS/MS方法，用于婴儿配方食品中B族维生素的高效、常规和稳定的色谱分析。很宽浓度范围内的八种水溶性维生素被鉴定出来，并在4分钟内定量。结果表明，保留时间重复性好，该方法能够在0.5 ppb的浓度下检测维生素B12，远低于婴儿配方奶粉中预期水平的约2 ppb。
本文提出了一种快速、灵敏的LC/MS/MS方法。
继2018年加拿大娱乐性大麻使用合法化之后，大麻产品的质量和安全性受到了极大关注。加拿大卫生部制定了一项监管计划，要求对所有大麻制品进行农药检测。根据该计划，加拿大大麻制品的许可生产商（LPs）必须向独立实验室发送具有代表性的产品样本，以便进行农药筛查和定量分析。本文阐述了利用ESI和APCI两种模式的LC/MS/MS分析大麻花中96种农药的一种稳健和可靠的方法。该方法不仅提供超低的检测限（同等或低于加拿大卫生部监管水平），而且与其他可用方法相比，效率显著提高。只需将LC/MS/MS与ESI和APCI模式结合使用来分析所有96种受管制农药，而无需进行GC/MS/MS和LC/MS/MS分析，为操 ...
兽药在畜牧生产中用于治疗疾病，预防感染和保护动物的生长，这有助于提供高质量的市场。然而，不加控制的使用可能会导致严重的人类疾病，因此世界各地的监管机构都制定了食品中兽药的最大残留量（MRL）或耐受量。由于样品基质的复杂性和不同化学性质分析物的多样性，兽药残留分析通常具有挑战性。本研究中，采用溶剂萃取结合液相色谱-质谱联用技术，建立了鸡肉样品中73种兽药（包括13种不同化学类别）的快速、灵敏、选择性分析方法。
以猪肉特有的三种肽为生物标志物，建立了一种选择性、灵敏的LC/MS/MS快速鉴定和分析肉样的方法。优化后的样品制备方法简单易行，可用于生、熟、加工肉制品的分析。该方法可以在1%w/w（10mg/g）的阈值检测范围内选择性地检测各种食品猪肉中的肽，因此该方法可用于清真食品（或猪肉相关食品）样品的分析。
由于具有选择性高、灵敏度高、适用于多种样品基质中多种化合物的分析等优点，液相色谱-串联质谱法（LC/MS/MS）已成为农药分析的首选方法。本研究采用改进的QuEChERS提取法与LC/MS/MS联用，建立了一种快速、灵敏、选择性好的多残留分析方法，对大米中200多种农药进行了分析。采用QSight®三重四极杆质谱仪中的时间管理MRM™，可为目标分析物多个MRM通道自动分配最佳驻留时间。这不仅节约了方法开发的时间，也提高了数据质量和分析性能，这些在本研究中的大米样品中多农药残留分析结果有具体展示。
塑料是当今全球使用量最多的材料之一。它们已广泛融入现代工业和商业生活方式，几乎对每类产品都做出了不可替代的重大贡献。
您将在本纲要中了解聚合物、塑料、橡胶和先进材料的广泛应用，以及这些应用如何简化您的工作并提升效率。
葡萄是世界上消费量最大的水果作物之一。葡萄既可作为新鲜产品也可作为加工产品消费，如葡萄酒、果酱、果汁、果冻、葡萄籽提取物、葡萄干、醋和葡萄籽油。在葡萄的整个生长季节，各种各样的杀虫剂被使用以控制葡萄园的病虫害和提高作物产量。由于大多数国家越来越严格的法规和安全标准，农药残留是葡萄产业利益相关者最为关注的问题。
最近在欧洲召回受污染的鸡蛋引起了对氟虫腈中毒的严重健康担忧。氟虫腈是一种剧毒杀虫剂，用于保护农作物。美国环保署已将氟虫腈列为C组致癌物。在这项研究中，我们描述了一种快速、可靠的分析方法，采用PerkinElmer QSight 200系列LC/MS/MS三重四极杆仪器对氟虫腈及其代谢物进行鉴定。结果表明，该方法具有极佳的回收率、线性、重现性和超高灵敏度。三步法样品制备过程快速简便，LC/MS/MS分析时间可在6分钟内完成，所有分析物的分离度都很高。
QSight-LC/MS/MS分析无需样品制备的葡萄酒中痕量农药。
为了保护人类健康，世界各地的监管机构制定了食品中兽药的最大残留水平（MRL）或允许水平。根据监管要求，使用高灵敏度和选择性的技术对四环素进行准确监测对保护人类健康至关重要。本研究提出了一种快速、灵敏的UHPLC/MS/MS方法用于肉类中四环素类抗生素的定量分析。 为了提高实验室生产率，QS Works采用了高通量自动进样器，因为它具有大容量、温控托盘和机械臂，可以长时间无人操作。QS works还允许实验室按顺序运行多达600个样本，从而提高测试实验室的效率。所开发的方法具有良好的灵敏度、线性、回收率、精密度和选择性，用于分析世界上不同监管机构设定的低耐受水平的肉类中的四环素。 ...
In this study we show two methods for the analysis of over 30 antibiotics and veterinary drugs in milk regulated by the Food Safety and Standards Authority of India (FSSAI). For polar analyte analysis, such as aminoglycoside antibiotics (apramycin, spectinomycin, and neomycin) in milk, a mixed mode ...
This application note highlights the LC/MS/MS analysis of PFAS compounds according to the European Union Water Framework Directive 2020/2184. It demonstrates how the PerkinElmer QSight® 420 LC/MS/MS System using a large volume direct injection can determine and quantify the latest 20 PFAS compounds ...
Governing bodies have implemented various directives to monitor acrylamide in drinking water. This also applies in the European Union where the water framework directive and subsequent daughter directives have defined many priority substances, including acrylamide. Compounds chlorate, perchlorate an ...
A simple and sensitive method for the simultaneous determination of plant growth regulators
Several directives throughout the EU provide guidance on environmental quality standards for water, and define more than 30 priority substances as significant risk to humans. Many of the monitoring limits within these directives are set at low µg/L (ppb) levels, and as such, require highly sensitive ...
Sensitive and accurate determination of remdesivir and GS-441524 in human plasma samples for pharmacokinetic and pharmacodynamic studies of remdevisir.
Since 2003 the usage of azo and non-azo dyes for food coloring has been declared as illegal by many of the food international authorities across the globe. That is because these substances such as Sudan I,II,III,IV and Rhodamine B, are potentially carcinogens and genotoxin in nature. As of now, no o ...
Discover a fast and reliable UHPLC-MS/MS method for the determination of HVA, VMA, and 5-HIAA acid in urine using the QSight 200 series mass spectrometer and a commercially available kit.
Simultaneous detect and quantify cortisol and cortisone in urine using the QSight 200 series mass spectrometer coupled with a commercially available kit.
Per- and polyfluoroalkyl substances (PFAS) are a group of synthetic chemicals developed in the 1940s, and widely used for their surfactant properties. Due to their prevalent use within consumer products and persistence in nature, PFAS have leached into the air, soil, and water, making exposure wides ...
Quantitative analysis of cell culture media components is a critical step in upstream bioprocess development. A comprehensive and quantitative understanding of cellular metabolic components could lead to a greater understanding of the process impacts on cell growth, productivity, and product quality ...
Growing health concerns regarding PFAS and their prevalence in consumer goods and the environment indicate a critical need to execute existing and upcoming regulatory methods simply and reliably on commercially available instrumentation. The United States Environmental Protection Agency (EPA) has es ...
This application note details an online-SPE-LC/MS/MS method for the determination of polycyclic aromatic hydrocarbons (PAHs) in drinking water samples which reaches the low detection levels required by EU regulations. The method couples the SP50 UHPLC system to the QSight® 400 series triple-quad mas ...
Ion Transmission Through a Quadrupole Ion Guide Under the Combined Influence of Viscous Flow and RF
Demand for cannabis testing services continues to climb as more US states and countries around the globe implement regulated adult-use markets. The cannabis testing sector in the US, like many facets of the cannabis industry, is challenged by the complexity of working with a federally illegal but st ...
The COVID-19 pandemic impacted industries, economies, and lives, and brought about the need for a new approach for contract testing laboratories working in different application fields. Considering the directions shaping the laboratory industry, this article revises trends that could be also applied ...
