The QSight LC/MS/MS System provides the capability and confidence required to analyze the most complex food and environmental samples. With high level of sensitivity and throughput, laboratories can meet even the most stringent regulatory requirements rapidly, easily, and effectively
| 型号名称 | QSight 420 LC/MS/MS |
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Over the past decade, awareness and concern about Per- and Polyfluoroalkyl Substances (PFAS) has grown and led to more in-depth analysis of these compounds and the effects that they can have on human health. Due to their inert nature, PFASs are persistent organic pollutants and have been found to ac ...
Analytical laboratories face many challenges when analyzing contaminants such as Pesticides, PFAS, mycotoxins in complex matrices. These samples often require time-consuming sample prep and regular maintenance of the analytical technology.
Due to PFAS persistence in the environment and potential health risks, regulations have been undergoing constant change and refinement.
With our extended portfolio of cannabis testing products featuring best-in-class sample homogenization platforms, ICP-MS, LC/MS-MS, Headspace-GCMS, UHPLC and FTIR instruments and consumables, we help drive analytical best practices and operating procedur
PFAS matrix-induced contamination poses various challenges for analytical laboratories, from the risk of achieving low detection limits and lab downtime.
PFAS compounds are ubiquitous throughout the environment and accumulate everywhere, including in the lab.
As per- and polyfluoroalkyl compounds become more prominent, the US Environmental Protection Agency (EPA) are developing more stringent regulations for PFAS monitoring.
Stricter regulations demanding lower detection limits, increased throughput and efficiency demand that labs need an LC/MS/MS solutions that offers robust and reliable performance while ensuring efficiencies.
When examining complex compounds like PFAS, pesticides, and mycotoxins using LC/MS/MS in challenging matrices, laboratories encounter issues such as system contamination, matrix effects, and the laborious task of source cleaning.
The PerkinElmer QSight LC/MS/MS is used for many applications, including forensic toxicology.
In this presentation, prepare to learn all of the best practices for Liquid Chromatography Mass Spectrometry from consumables all the way to instrumentation and analysis. This talk is well-suited for all LC/MS applications including environmental testing
In this latest webinar, LC–MS/MS PerkinElmer expert Dr. Avinash Dalmia describes how LC–MS/MS based systems and methods can overcome the challenges associated with the analysis of pesticides and mycotoxins regulated by Colorado state in hemp with dual ES
Growing environmental concern has led to stricter regulations of drinking water and water supplies over the past decade including routine monitoring and detection of cyanotoxins resulting from ever-growing algae blooms. This talk discusses the utiliza
PerkinElmer offers a portfolio of high-performance solutions to optimize your laboratory workflow for PFAS analysis.
Pharmaceutical and personal care products (PPCPS) are an emerging environmental concern and include human and veterinary prescriptions, over-the-counter medications, sunscreens, lotions, soaps and insect repellents. In this webinar we demonstrate the a
In this podcast, we meet with Simone Rumph, a first generation college student, to discuss her research on post-mortem drug identification.
In this short webinar, PerkinElmer’s Environmental Leader, Tom Hey, discusses simplified PFAS method implementation with the comprehensive PerkinElmer LC/MS/MS workflow, featuring ready-to use consumables kits, reagents and software-driven compliance.
Emerging contaminants, including perfluoroalkyl surfactants (PFAS) and Pharmaceuticals and Personal Care Products (PPCPs), have garnered increasing interest in recent years as their bioaccumulative nature and endocrine disrupting potential have become..
When it comes to analyzing environmental or food samples, including water, soil, cannabis or any solid matrices, labs need to meet stricter regulations that demand lower detection limits.
The US EAP Method 537.1 is used for the determination of selected PFASs in drinking water by solid phase extraction and liquid chromatography/tandem mass spectrometry. This talk discusses the utilization of the PerkinElmer QSight® Triple Quadrupole LC
农药可以通过我们食用的食物对人类健康产生不利影响，也可以渗入土壤和地下水并通过环境影响我们。为了适应复杂且不断变化的监管环境，您的农药分析解决方案需要跟上您不断增长的样本量。
When analyzing food and environmental samples, laboratories often need multiple system to get the qualitative and quantitative information on contaminants. But this can result in duplicated sample preparation processes, increased cost of ownership – and suboptimal lab efficiency. Discover the unique ...
Our modular Simplicity 3Q™ software is ideal for acquiring, quantifying and reporting
在养蜂业中，磺胺类药物是治疗美国和欧洲臭虫病（一种感染蜜蜂的疾病）的最常用抗生素。本应用说明介绍了QSight 200系统如何为蜂蜜中磺胺类药物的分析提供一个非常灵敏和可靠的平台。
随着一些美国的州和省通过了药用和娱乐用途合法化的新法规，大麻浓缩物和CBD产品（食用食品、主题食品、电子烟产品等）的使用越来越受欢迎。确保大麻产品中杀虫剂和真菌毒素水平低于监管水平的测试至关重要，然而，大麻浓缩物基质存在许多分析挑战，包括样品基质效应更高和样品中大麻素浓度增加。在本应用说明中，提出了一种用于分析大麻浓缩物基质中66种农药（包括通常通过GC/MS/MS分析的疏水性和含氯农药）和5种真菌毒素的LC/MS/MS方法。利用配置有APCI和ESI双源的QSight®420 LC/MS/MS仪器，分析回收率良好且检测限低于加利福尼亚州大麻法规规定的标准。 ...
兽药在畜牧生产中用于治疗疾病，预防感染和保护动物的生长，这有助于提供高质量的市场。然而，不加控制的使用可能会导致严重的人类疾病，因此世界各地的监管机构都制定了食品中兽药的最大残留量（MRL）或耐受量。由于样品基质的复杂性和不同化学性质分析物的多样性，兽药残留分析通常具有挑战性。本研究中，采用溶剂萃取结合液相色谱-质谱联用技术，建立了鸡肉样品中73种兽药（包括13种不同化学类别）的快速、灵敏、选择性分析方法。
以猪肉特有的三种肽为生物标志物，建立了一种选择性、灵敏的LC/MS/MS快速鉴定和分析肉样的方法。优化后的样品制备方法简单易行，可用于生、熟、加工肉制品的分析。该方法可以在1%w/w（10mg/g）的阈值检测范围内选择性地检测各种食品猪肉中的肽，因此该方法可用于清真食品（或猪肉相关食品）样品的分析。
由于具有选择性高、灵敏度高、适用于多种样品基质中多种化合物的分析等优点，液相色谱-串联质谱法（LC/MS/MS）已成为农药分析的首选方法。本研究采用改进的QuEChERS提取法与LC/MS/MS联用，建立了一种快速、灵敏、选择性好的多残留分析方法，对大米中200多种农药进行了分析。采用QSight®三重四极杆质谱仪中的时间管理MRM™，可为目标分析物多个MRM通道自动分配最佳驻留时间。这不仅节约了方法开发的时间，也提高了数据质量和分析性能，这些在本研究中的大米样品中多农药残留分析结果有具体展示。
塑料是当今全球使用量最多的材料之一。它们已广泛融入现代工业和商业生活方式，几乎对每类产品都做出了不可替代的重大贡献。
您将在本纲要中了解聚合物、塑料、橡胶和先进材料的广泛应用，以及这些应用如何简化您的工作并提升效率。
葡萄是世界上消费量最大的水果作物之一。葡萄既可作为新鲜产品也可作为加工产品消费，如葡萄酒、果酱、果汁、果冻、葡萄籽提取物、葡萄干、醋和葡萄籽油。在葡萄的整个生长季节，各种各样的杀虫剂被使用以控制葡萄园的病虫害和提高作物产量。由于大多数国家越来越严格的法规和安全标准，农药残留是葡萄产业利益相关者最为关注的问题。
丙烯酰胺是一种可能致癌的有机化合物，存在于一些高温烹调的食物中。它源于氨基酸天冬酰胺和葡萄糖发生美拉德反应。2002年，在炸薯条和烤面包中发现了丙烯酰胺。这种化合物现在也在一些其他食物中被发现，如咖啡、黑橄榄、干梨和花生。结果是世界卫生组织立即限制了它在食品中的存在。
随着《2018年农业改良法案》的通过，为大麻二酚（CBD）提取而进行的大麻产品农业种植在美国合法化。自该法案通过以来，对大麻生产中杀虫剂的使用备受关注。然而，美国目前没有联邦指南来标准化大麻制品中农药残留的检测和定量分析方法。 在该应用文献中，介绍了一种一针进样同时测定66种杀虫剂的稳健高效的LC/MS/MS方法，且分析物涵盖了常规情况下需要采用GC/MS/MS分析的部分疏水性农药和含氯农药。采用PerkinElmer QSight®420 (UHPLC和MS/MS检测器，双ESI/APCI源) ，可获得70-120%范围内的优良回收率。文献中还概述了参加Emerald Scientific盲 ...
QSight-LC/MS/MS分析无需样品制备的葡萄酒中痕量农药。
独特层流气离子导向技术UHPLC-ESI-MS/MS分析浆果中目标农药残留
In this study we show two methods for the analysis of over 30 antibiotics and veterinary drugs in milk regulated by the Food Safety and Standards Authority of India (FSSAI). For polar analyte analysis, such as aminoglycoside antibiotics (apramycin, spectinomycin, and neomycin) in milk, a mixed mode ...
Ochratoxin A (OTA) is a secondary metabolite produced by Penicillium and Aspergillus fungi species found in soil and organic matter, and is one of the most widely reported of the nearly 400 recognized mycotoxin contaminants of agricultural products. OTA can enter the human food chain through contami ...
This application note presents a sensitive and reliable LC/MS/MS method using the PerkinElmer QSight
A simple and sensitive method for the simultaneous determination of plant growth regulators
Several directives throughout the EU provide guidance on environmental quality standards for water, and define more than 30 priority substances as significant risk to humans. Many of the monitoring limits within these directives are set at low µg/L (ppb) levels, and as such, require highly sensitive ...
Sensitive and accurate determination of remdesivir and GS-441524 in human plasma samples for pharmacokinetic and pharmacodynamic studies of remdevisir.
Cyanotoxins often exist intracellularly in cyanobacteria and are released into the water when cells die. Blooms caused by cyanobacteria can be harmful to the human health, animals, and the environment. Microcystin-LR (MC-LR) is one of the most common cyanotoxins and ingestion will cause negative hum ...
Since 2003 the usage of azo and non-azo dyes for food coloring has been declared as illegal by many of the food international authorities across the globe. That is because these substances such as Sudan I,II,III,IV and Rhodamine B, are potentially carcinogens and genotoxin in nature. As of now, no o ...
Mycotoxins are toxic secondary metabolites produced by various fungal species growing in foods and animal feeds. To minimize risk and protect consumers, mycotoxin levels in foods and/or feeds have been regulated by agencies in many countries around the world. A number of analytical methods for the d ...
Per- and polyfluoroalkyl substances (PFAS) are man-made carbon-chain based compounds that have been widely used in commercial and industrial products such as fire-fighting foams, water proofing treatments for clothing and furniture, nonstick cookware, and paper. PFAS’ are thermally and chemically st ...
This application note outlines a new workflow with one instrument platform (LC/MS/MS) method that is ideal for simultaneous analysis of pesticide and mycotoxins residue in cannabis. This application note demonstrates the performance of a LC/MS/MS ESI and APCI method with a single solvent extraction ...
This application note describes a novel LC/MS/MS method with dual ESI and APCI source for analysis of different pesticides and mycotoxins residues regulated by seven different states in cannabis samples as of June 2021. The straightforward sample preparation procedure allows to achieve short sample ...
Tobacco specific nitrosamines (TSNA) are a group of chemicals found in tobacco, smokeless tobacco, and tobacco smoke. They are widely considered to be among the most important arcinogens in tobacco products and cigarette smoke. Tobacco product manufacturers must report their contents in tobacco prod ...
Per- and polyfluoroalkyl substances (PFAS) are a group of synthetic chemicals developed in the 1940s, and widely used for their surfactant properties. Due to their prevalent use within consumer products and persistence in nature, PFAS have leached into the air, soil, and water, making exposure wides ...
Quantitative analysis of cell culture media components is a critical step in upstream bioprocess development. A comprehensive and quantitative understanding of cellular metabolic components could lead to a greater understanding of the process impacts on cell growth, productivity, and product quality ...
EU water policies are reevaluated on a consistent basis to ensure water sources do not contain contaminants at levels above regulatory levels. As regulations are reviewed, regulatory limits are often lowered, and analytical techniques must adapt to meet the new stringent requirements. In this applic ...
Growing health concerns regarding PFAS and their prevalence in consumer goods and the environment indicate a critical need to execute existing and upcoming regulatory methods simply and reliably on commercially available instrumentation. The United States Environmental Protection Agency (EPA) has es ...
Per- and polyfluoroalkyl substances (PFAS) are a diverse group of synthetic organic compounds which have been utilized as aqueous film forming foams (AFFF) for firefighting purposes, and as stain and water resistant coatings on a number of consumer products such as clothing, furniture or cookware. P ...
A New, Sensitive Method for Lignan Metabolite Detection of Flaxseed-Fed Mice Using LC/MS/MS
This application note details an online-SPE-LC/MS/MS method for the determination of polycyclic aromatic hydrocarbons (PAHs) in drinking water samples which reaches the low detection levels required by EU regulations. The method couples the SP50 UHPLC system to the QSight® 400 series triple-quad mas ...
Ion Transmission Through a Quadrupole Ion Guide Under the Combined Influence of Viscous Flow and RF
Simulation using sophisticated modeling techniques has become a powerful tool for mass spectrometry
Infographic Poster showing the range of different analytical solutions for Toxicology Labs; from GC and LC, to ICP-MS and UV-Vis. Benchtop and floor standing chromatography, spectroscopy and thermal solutions for everyday robust and reliable analyses. FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC ...
