More than ever, laboratories analyzing food and environmental samples are faced with evolving challenges with stricter regulations demanding lower detection limits and higher levels of productivity. Lab operations need to be optimized, without any compromise on analysis confidence and accuracy.
With the PerkinElmer QSight® Triple Quad LC/MS/MS labs can test for the most challenging samples with maximized uptime and confidence. The unique dual-source configuration enables high-throughput labs to collect data in two complementary modes, maximizing the output from a single injection. Combined with the StayClean™ technology dramatically reduced source cleaning and maintenance, translating into higher productivity and high ROI. Running on the PerkinElmer Simplicity™ 3Q Software, the PerkinElmer QSight Triple Quad LC/MS/MS is easy-to-learn and use and it is a complete solution streamlining the complete workflow, from validated method development to data reporting.
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The QSight LC/MS/MS System provides the capability and confidence required to analyze the most complex food and environmental samples. With high level of sensitivity and throughput, laboratories can meet even the most stringent regulatory requirements rapidly, easily, and effectively
Model Name | QSight 420 LC/MS/MS |
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Mycotoxins are toxic secondary metabolites produced by various fungal species growing in foods and animal feeds. To minimize risk and protect consumers, mycotoxin levels in foods and/or feeds have been regulated by agencies in many countries around the world. A number of analytical methods for the d ...
Per- and polyfluoroalkyl substances (PFASs), or Per- and polyfluorinated compounds (PFCs), represent a group of anthropogenic chemicals that have been produced and widely used in industrial applications and consumer products since the 1950s. The unique physical and chemical characteristics of these ...
Testing for the levels of pesticide and mycotoxins in cannabis is important to ensure consumer safety and quality control. In this work, the PerkinElmer application development team analyzed all 66 pesticides (including very hydrophobic and chlorinated pesticides typically analyzed by GC-MS/MS) and ...
Acrylamide is a probable carcinogen organic compound that is found in some foods that are cooked at elevated temperatures. It’s origins are due to the condensation of the amino acid asparagine and glucose as part of Maillard reaction. In 2002, Acrylamide was found to be present in french fries and b ...
Aflatoxin B1 is considered to be the most genotoxic of the mycotoxins, and, when ingested by cows, is converted to aflatoxin M1 which has been shown to cause liver cancer in certain animals.
Due to the large number of pesticides potentially used in rice production, the use of multi-residue methods capable of determining many pesticides in one single run is the most efficient approach. In this study, a fast, sensitive and selective multiresidue method has been developed for analysis of o ...
Liquid chromatography-tandem mass spectrometry (LC/MS/MS) has become the method of choice for pesticide. The state of Oregon has issued regulatory limits for 59 pesticide residues in both cannabis flower and concentrates, while other states have come up with their own lists of pesticide residues rel ...
This application note details an online-SPE-LC/MS/MS method for the determination of polycyclic aromatic hydrocarbons (PAHs) in drinking water samples which reaches the low detection levels required by EU regulations. The method couples the SP50 UHPLC system to the QSight® 400 series triple-quad mas ...
A selective and sensitive LC/MS/MS method for fast identification and analysis of meat samples using three peptides specific for pork as biomarkers. . The optimized sample preparation procedure is easy to follow and can be used for analyzing raw, cooked and processed meat products. This method can s ...
In order to protect human health, regulatory agencies around the world have established maximum residue levels (MRLs) or tolerances of veterinary drugs in foods. The use of highly sensitive and selective techniques for accurate monitoring of tetracyclines based on regulatory requirements is essentia ...
With routine labs tasked with the analysis of larger and larger target lists, and with greater numbers of samples requiring analysis, we deployed simple sample preparation protocols such as solvent extraction to meet the need of high sample throughput with lower cost. In this work, we demonstrate ho ...
The increasing demand for organic products, evolving global regulations, and improving accessibility of agricultural hubs to global markets results in pressure on food safety precautions. Translating, in part, to increased pesticide residue analysis demand. Mass spectrometry meets pesticide analysis ...
Fipronil is a broad-spectrum phenylpyrazole insecticide almost used to protect corps from insects but also to treat lice and ticks in chickens. The U.S. EPA classified fipronil as Group C, possible human carcinogen, therefore International organizations defined admissible limits for the fipronil usa ...
Aflatoxin B1 is often found in animal feeds such as corn, cottonseed cake, groundnut meal, and other agricultural commodities. When these contaminated feeds are ingested by milk-producing animals, such as cattle, aflatoxin B1 can be converted to aflatoxin M1 (a hydroxy derivate of aflatoxin B1) by o ...
In this study we show two methods for the analysis of over 30 antibiotics and veterinary drugs in milk regulated by the Food Safety and Standards Authority of India (FSSAI). For polar analyte analysis, such as aminoglycoside antibiotics (apramycin, spectinomycin, and neomycin) in milk, a mixed mode ...
In apiculture, sulfonamides are the most commonly used antibiotics to treat American and European Foulbrood, a type of disease that infects bees. This application note demonstrates how QSight 200 System can provides a very sensitive and robust platform for the analysis of sulfonamides in honey.
Glyphosate is a very polar compound with high solubility in water and low solubility in most organic solvents and, as such, requires methods based on derivatization which are labor-intensive and time consuming. The present work shows a 12 minute LC-MS/MS method with an amino-based column to analyze ...
Quantitative analysis of cell culture media components is a critical step in upstream bioprocess development. A comprehensive and quantitative understanding of cellular metabolic components could lead to a greater understanding of the process impacts on cell growth, productivity, and product quality ...
Estrogen plays an important role in the human body, but excess concentrations of endogenous estrogens, a known endocrine disrupting compound (EDC), in urine have been linked to the development and growth of breast cancer and tumors in females. Endogenous estrogens, including estrone (E1), 17ß-estrad ...
Per- and polyfluoroalkyl substances (PFAS) are a group of synthetic chemicals developed in the 1940s, and widely used for their surfactant properties. Due to their prevalent use within consumer products and persistence in nature, PFAS have leached into the air, soil, and water, making exposure wides ...
Discover a fast and reliable UHPLC-MS/MS method for the determination of HVA, VMA, and 5-HIAA acid in urine using the QSight 200 series mass spectrometer and a commercially available kit.
Sensitive and accurate determination of remdesivir and GS-441524 in human plasma samples for pharmacokinetic and pharmacodynamic studies of remdevisir.
Following the 2018 legalization of recreational cannabis usage in Canada, the quality and safety of cannabis products has garnered significant attention. Health Canada has developed a regulatory program mandating pesticide testing on all cannabis products. Under the program, licensed producers (LPs) ...
EU water policies are reevaluated on a consistent basis to ensure water sources do not contain contaminants at levels above regulatory levels. As regulations are reviewed, regulatory limits are often lowered, and analytical techniques must adapt to meet the new stringent requirements. In this applic ...
Cyanotoxins often exist intracellularly in cyanobacteria and are released into the water when cells die. Blooms caused by cyanobacteria can be harmful to the human health, animals, and the environment. Microcystin-LR (MC-LR) is one of the most common cyanotoxins and ingestion will cause negative hum ...
This application note describes a novel LC/MS/MS method with dual ESI and APCI source for analysis of different pesticides and mycotoxins residues regulated by seven different states in cannabis samples as of June 2021. The straightforward sample preparation procedure allows to achieve short sample ...
Haloacetic acids (HAAs) are a class of undesired by-products resulting from the reaction of chlorinated disinfectants with natural organic matter in water, Which is known to be carcinogenic. The Japan Ministry of Health revised the inspection method for HAAs, which led to expansion of the analytical ...
Ochratoxin A (OTA) is a secondary metabolite produced by Penicillium and Aspergillus fungi species found in soil and organic matter, and is one of the most widely reported of the nearly 400 recognized mycotoxin contaminants of agricultural products. OTA can enter the human food chain through contami ...
Wine can often contain pesticides and fungicides that have been sprayed on the fruits during their growing period. In addition to these contaminants, wine can also contain additives that have been deliberately added during production processes to improve its flavor and color. In this study, a simple ...
In this study, the QSight LC-MS/MS system was used to evaluate the potential of eliminating sample preparation for trace level pesticide analysis in a complex sample such as wine. We injected undiluted red and white wine samples into the mass spectrometer and studied reproducibility in analysis of t ...
The COVID-19 pandemic impacted industries, economies, and lives, and brought about the need for a new approach for contract testing laboratories working in different application fields. Considering the directions shaping the laboratory industry, this article revises trends that could be also applied ...
Pesticides can adversely affect human health through the food we consume but can also leach into soil and groundwater and impact us through the environment. To keep up with a complex and constantly changing regulatory environment, your pesticide analysis solution needs to keep up with your burgeonin ...
This poster lays out our whole material characterization range for the analysis of polymers and plastics. Find ideal techniques and instruments at each stage in the polymer manufacturing process: Resin Development - Resin Manufacture - Compound Development - Compound Manufacture - Product Forming - ...
Our modular Simplicity 3Q™ software is ideal for acquiring, quantifying and reporting
Lab reequirements for QSight triple quad LC/MS/MS systems, including storage, suppleis, space, electrical, power, gas supply requirements
Product Certificate for the QSight 300/400 Series
Simulation using sophisticated modeling techniques has become a powerful tool for mass spectrometry
Ion Transmission Through a Quadrupole Ion Guide Under the Combined Influence of Viscous Flow and RF
Theoretical Studies of Swirling Flow and Heating Methods on Droplet Evaporation in a Heated Coaxial
Analytical laboratories face many challenges when analyzing contaminants such as Pesticides, PFAS, mycotoxins in complex matrices. These samples often require time-consuming sample prep and regular maintenance of the analytical technology.
Due to PFAS persistence in the environment and potential health risks, regulations have been undergoing constant change and refinement.
With our extended portfolio of cannabis testing products featuring best-in-class sample homogenization platforms, ICP-MS, LC/MS-MS, Headspace-GCMS, UHPLC and FTIR instruments and consumables, we help drive analytical best practices and operating procedur
PFAS matrix-induced contamination poses various challenges for analytical laboratories, from the risk of achieving low detection limits and lab downtime.
PFAS compounds are ubiquitous throughout the environment and accumulate everywhere, including in the lab.
As per- and polyfluoroalkyl compounds become more prominent, the US Environmental Protection Agency (EPA) are developing more stringent regulations for PFAS monitoring.
Stricter regulations demanding lower detection limits, increased throughput and efficiency demand that labs need an LC/MS/MS solutions that offers robust and reliable performance while ensuring efficiencies.
When examining complex compounds like PFAS, pesticides, and mycotoxins using LC/MS/MS in challenging matrices, laboratories encounter issues such as system contamination, matrix effects, and the laborious task of source cleaning.
The PerkinElmer QSight LC/MS/MS is used for many applications, including forensic toxicology.
In this presentation, prepare to learn all of the best practices for Liquid Chromatography Mass Spectrometry from consumables all the way to instrumentation and analysis. This talk is well-suited for all LC/MS applications including environmental testing
In this latest webinar, LC–MS/MS PerkinElmer expert Dr. Avinash Dalmia describes how LC–MS/MS based systems and methods can overcome the challenges associated with the analysis of pesticides and mycotoxins regulated by Colorado state in hemp with dual ES
Growing environmental concern has led to stricter regulations of drinking water and water supplies over the past decade including routine monitoring and detection of cyanotoxins resulting from ever-growing algae blooms. This talk discusses the utiliza
PerkinElmer offers a portfolio of high-performance solutions to optimize your laboratory workflow for PFAS analysis.
Pharmaceutical and personal care products (PPCPS) are an emerging environmental concern and include human and veterinary prescriptions, over-the-counter medications, sunscreens, lotions, soaps and insect repellents. In this webinar we demonstrate the a
In this podcast, we meet with Simone Rumph, a first generation college student, to discuss her research on post-mortem drug identification.
In this short webinar, PerkinElmer’s Environmental Leader, Tom Hey, discusses simplified PFAS method implementation with the comprehensive PerkinElmer LC/MS/MS workflow, featuring ready-to use consumables kits, reagents and software-driven compliance.
Emerging contaminants, including perfluoroalkyl surfactants (PFAS) and Pharmaceuticals and Personal Care Products (PPCPs), have garnered increasing interest in recent years as their bioaccumulative nature and endocrine disrupting potential have become..
When it comes to analyzing environmental or food samples, including water, soil, cannabis or any solid matrices, labs need to meet stricter regulations that demand lower detection limits.
The US EAP Method 537.1 is used for the determination of selected PFASs in drinking water by solid phase extraction and liquid chromatography/tandem mass spectrometry. This talk discusses the utilization of the PerkinElmer QSight® Triple Quadrupole LC
Per- and polyfluoroalkyl substances (PFAS) have gained significant attention as an emerging environmental and safety threat in the United States. Since the 1940s, PFAS are ubiquitous in industrial usage due to their chemical stability, thermal stability, and high resistance to degradation. Bioaccumu ...